Deferiprone‐induced agranulocytosis: 20 years of clinical observations

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Deferiprone‐induced agranulocytosis: 20 years of clinical observations

Use of the iron chelator deferiprone for treatment of iron overload in thalassemia patients is associated with concerns over agranulocytosis, which requires weekly absolute neutrophil counts (ANC). Here, we analyze all episodes of agranulocytosis (n = 161) and neutropenia (n = 250) during deferiprone use in clinical trials (CT) and postmarketing surveillance programs (PMSP). Rates of agranulocy...

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ژورنال

عنوان ژورنال: American Journal of Hematology

سال: 2016

ISSN: 0361-8609,1096-8652

DOI: 10.1002/ajh.24479